Murdoch Childrens Research Institute
Browse

Genotype informed Bayesian dosing of tacrolimus in solid organ transplant- Pharmacogenomic Implementation in Children

Posted on 2025-01-28 - 23:39 authored by MCRI REDCap ServiceAccount
The BRUNO-PIC study is a retrospective/prospective study looking at tacrolimus in our solid organ transplantation in the paediatric population. We will compare the current practise at RCH, where all doses of tacrolimus is prescribed at a standard dose then adjusted based on levels on a trial-and-error approach to reach the target concentration (retrospective) compared to using genotyping and Bayesian estimation to have a more targeting approach of prescribing tacrolimus post solid organ transplantation (prospective).

CITE THIS COLLECTION

DataCite
No result found
or
Select your citation style and then place your mouse over the citation text to select it.

Project Identifier

ETH02699

Data Steward

dhrita.khatri

Data Controller

rachel.conyers

HREC Number

ETH02699

Data Retention

Retention period: 15; Destruction plan: All data other then genomic sequencing data will be destroyed in line with MCRI's SOP for data destruction at the time of destruction as destruction procedures may change over time.

Storage Location(s)

Long-term storage location(s): HS - MCRI OneDrive, HS - MCRI SharePoint / Intranet, HS - REDCap; Network folder:

SHARE

email

Usage metrics

MCRI Data Catalog

AUTHORS (2)

CATEGORIES

need help?